Bioinformatics and computational biology in drug discovery and development / (Record no. 44680)
[ view plain ]
| 000 -LEADER | |
|---|---|
| fixed length control field | 02688nam a22002298i 4500 |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER | |
| ISBN | 9780521768009 (hardback) |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER | |
| ISBN | 0521768004 |
| 082 00 - DEWEY DECIMAL CLASSIFICATION NUMBER | |
| Classification number | 615.19 |
| Item number | BIO |
| 100 ## - MAIN ENTRY--AUTHOR NAME | |
| Personal name | Loging, William T., |
| Relator term | Editor |
| 245 00 - TITLE STATEMENT | |
| Title | Bioinformatics and computational biology in drug discovery and development / |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. (IMPRINT) | |
| Place of publication | Cambridge : |
| Name of publisher | Cambridge University Press, |
| Year of publication | 2016. |
| 300 ## - PHYSICAL DESCRIPTION | |
| Number of Pages | xi, 233 pages ; |
| 500 ## - GENERAL NOTE | |
| General note | Includes index |
| 505 8# - FORMATTED CONTENTS NOTE | |
| Formatted contents note | Machine generated contents note: Foreword; Preface: the future of drug discovery and health care / Eric Schadt; 1. The art and science of the Drug Discovery Pipeline (DDP) / William T. Loging; 2. Computational approaches to drug target identification / Thomas B. Freeman and Pek Lum; 3. Understanding human disease knowledge through text mining / Raul Rodriguez-Esteban; 4. Integrating translational biomarkers into drug development / Jonathan Phillips; 5. Computational phenotypic assessment of small molecules in drug discovery / William T. Loging and Thomas B. Freeman; 6. Data visualization and the DDP process / Ke Xu; 7. Information visualization - important IT considerations / Telmo Silva; 8. The New Drug Application (NDA) and regulatory approval stages / William T. Loging, Marilyn Lewis, Bryn Williams-Jones and Roy Mansfield; 9. Clinical trial failures and drug repositioning / Mark Crawford and Jeff Handler; Appendix I. Additional knowledge-based analysis approaches / Raul Rodriguez-Esteban; Appendix II. Open source tools and public data sources / Yirong Wang and William T. Loging; Index. |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc | "Computational biology drives discovery through its use of high-throughput informatics approaches. This book provides a road map of the current drug development process and how computational biology approaches play a critical role across the entire drug discovery pipeline. Through the use of previously unpublished, real-life case studies the impact of a range of computational approaches are discussed at various phases of the pipeline. Additionally, a focus section provides innovative visualisation approaches, from both the drug discovery process as well as from other fields that utilise large datasets, recognising the increasing use of such technology. Serving the needs of early career and more experienced scientists, this up-to-date reference provides an essential introduction to the process and background of drug discovery, highlighting how computational researchers can contribute to that pipeline"--Provided by publisher. |
| 650 12 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical Term | Drug Discovery |
| 650 22 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical Term | Biomarkers, Pharmacological. |
| 650 22 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical Term | Computational Biology |
| 650 22 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical Term | Data Mining |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Loging, William T., |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Koha item type | Reference Books |
| Collection code | Home library | Current library | Shelving location | Date acquired | Source of acquisition | Cost, normal purchase price | Full call number | Accession Number | Koha item type |
|---|---|---|---|---|---|---|---|---|---|
| Reference | Main Library | Main Library | Reference | 06/08/2019 | Purchased | 9926.64 | 615.19 BIO | 015891 | Reference Books |