000			02014pam a2200229 a 4500
020			_a9780632049837
020			_a0632049839
082	0	0	_a574.873282 _bPRI
100	1		_aPrimrose, S. B.
245	1	0	_aPrinciples of genome analysis :
250			_a2nd ed.
260			_aOxford ; _aMalden, MA : _bBlackwell Science, _c1998.
300			_ax, 193 pages : _billustrations (some color) ; 25 cm
500			_aIncluded index
505			_a1. Rationale for mapping and sequencing genomes -- 2. The organization and structure of genomes -- 3. Subdividing the genome -- 4. Assembling a physical map of the genome -- 5. Sequencing methods and strategies -- 6. Analysing sequence data -- 7. Finding genes in large genomes.
520			_aGenome analysis and genomics are at the forefront of current research in the life sciences. Since the first edition of Principles of Genome Analysis was published, the sequencing of genomes has continued apace, with the major landmark of the human genome sequence being achieved in 2001. Now the emphasis of biological research is on genomics: the understanding of gene function and the interaction of gene products at the whole genome level. As before, this book provides a step-by-step outline of the techniques involved in genome mapping and sequencing. Additionally, the text has been greatly expanded to cover sub-disciplines of genomics, revisions of sections on genome sequencing and bioinformatics, and new chapters on comparative genomics, functional genomics and proteomics. The book concludes with an exciting new chapter describing a variety of ways to utilize genome analysis and sequencing in biology, medicine and agriculture. Aimed at advanced undergraduates, this text will follow the same format as the highly successful Principles of Gene Manipulation by Primrose, Twyman and Old, now in its sixth edition.
650		0	_aGene mapping.
650		0	_aNucleotide sequence.
650	1	2	_aChromosome Mapping.
650	2	2	_aBase Sequence.
942			_cREF
999			_c36365 _d36365