000 02065cam a22002534a 4500
020 _a0521840988 (hardback)
020 _a0521600820 (pbk.)
020 _a9780521840989
020 _a9780521600828
082 0 0 _a572.80285
100 1 _aXiong, Jin.
245 1 0 _aEssential bioinformatics /
260 _aNew York :
_bCambridge University Press,
_c2006.
300 _axi, 339 p. :
_bill. (some col.) ;
500 _aIncludes index
505 0 _aIntroduction to biological databases -- Pairwise sequence alignment -- Database similarity searching -- Multiple sequence alignment -- Profiles and hidden Markov models -- Protein motifs and domain prediction -- Gene prediction -- Promoter and regulatory element prediction -- Phylogenetics basics -- Phylogenetic tree construction methods and programs -- Protein structure basics -- Protein structure visualization, comparision, and classification -- Protein secondary structure prediction -- Protein tertiary structure prediction -- RNA structure prediction -- Genome mapping, assembly, and comparison -- Functional genomics -- Proteomics.
520 _aA concise yet comprehensive textbook of bioinformatics, which provides a broad introduction to the entire field. Written specifically for a life science audience, the basics of bioinformatics are explained, followed by discussions of the state-of-the-art computational tools available to solve biological research problems. All key areas of bioinformatics are covered including biological databases, sequence alignment, genes and promoter prediction, molecular phylogenetics, structural bioinformatics, genomics and proteomics. The book emphasizes how computational methods work and compares the strengths and weaknesses of different methods.
650 0 _aBioinformatics.
650 1 2 _aComputational Biology.
856 4 1 _uhttp://www.loc.gov/catdir/toc/ecip061/2005029453.html
856 4 2 _uhttp://www.loc.gov/catdir/enhancements/fy0659/2005029453-d.html
856 4 2 _uhttp://www.loc.gov/catdir/enhancements/fy0733/2005029453-b.html
942 _cREF
999 _c44243
_d44243